Correlation analysis of liver tumor-associated genes with liver regeneration
نویسندگان
چکیده
منابع مشابه
Pregnancy, tumor growth, and liver regeneration.
We have previously reported observations on tumor growth in partially hepatectomized rats. These studies were undertaken to investigate the extent to which two rapidly growing tissues might compete for metabolic requirements for increased anabolic processes. In the case of tumor growth in the presence of regenerating liver after partial hepatectomy, no evidence for such com petition was found; ...
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The mammalian liver has a very strong regeneration capacity after partial hepatectomy (PH). To further learn the genes participating in the liver regeneration (LR), 551 cDNAs selected from subtracted cDNA libraries of the regenerating rat liver were screened by microarray, and their expression profiles were studied by cluster and generalization analyses. Among them, 177 genes were identified un...
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Mitochondria are closely associated with cell survival, and it is of interest to determine whether apoptosis pathways, which are mediated by mitochondria, are involved in liver regeneration (LR). To identify the mechanisms underlying mitochondria-mediated apoptosis during rat LR, we used the Rat Genome 230 2.0 Array to investigate changes in gene expression. Next, we searched the GO and NCBI da...
متن کاملPossible regulation of genes associated with intracellular signaling cascade in rat liver regeneration
OBJECTIVE The importance of signal transduction in cell activities has been generally accepted. The purpose of this study was to analyze the regulatory effect of intracellular signaling cascade-associated genes on rat liver regeneration (LR) at transcriptional level. MATERIAL AND METHODS The associated genes were originally obtained through a search of the databases and related scientific pub...
متن کاملLiver regeneration after liver transplantation.
BACKGROUND/PURPOSE The liver has a remarkable capacity to regenerate after injury or resection. The aim of this review is to outline the mechanisms and factors affecting liver regeneration after liver transplantation. METHODS Relevant studies were reviewed using Medline, PubMed and Springer databases. RESULTS A variety of cytokines (such as interleukin-6 and tumor necrosis factor-α), growth...
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ژورنال
عنوان ژورنال: World Journal of Gastroenterology
سال: 2007
ISSN: 1007-9327
DOI: 10.3748/wjg.v13.i24.3323